Etanercept (TNF-α inhibitor) vs saline for blast-induced tinnitus

Trial details

Registry identifier: NCT04066348 on ClinicalTrials.gov
Phase: Phase 2
Status: Recruiting
Sponsor: Wayne State University
Planned enrollment: 88
Estimated completion: Sep 2026 (re-check in Oct 2026)
Country: USA

Why this trial matters

Tests an anti-inflammatory mechanism in a defined subtype (blast-induced tinnitus) — primary completion is this month.

Related treatment evidence

See the current evidence for Off-label oral drugs (antidepressants, benzodiazepines, gabapentin, betahistine).

Trial statuses are verified against the ClinicalTrials.gov registry by our weekly automated check. A tracked trial is research in progress — inclusion is not a treatment recommendation, and only the study team can determine eligibility.