Prototype digital polytherapeutic for tinnitus: randomized single-blind controlled trial
Record details
- Authors: Searchfield GD, Sanders PJ.
- Journal / source: Frontiers in Neurology (2022)
- Design: Randomized single-blind controlled trial vs white-noise app
- Sample: 98 enrolled / 61 analyzed (31 vs 30)
- Primary endpoint: TFI
- Randomized: Yes · Sham/placebo-controlled: No · Independent of the manufacturer: Yes
What this research found
TFI −17.8 points (polytherapeutic) vs −10.1 (white-noise app); clinically meaningful response 65% vs 43%.
A prototype app trial with ~61 completers — the research ancestor of the TrueSilence commercial product, which has no product-level trials yet.
Limitations and conflicts of interest
Completer analysis; single-blind; prototype ≠ shipped product.
Funding / conflicts: Founder-led research (Searchfield later founded TrueSilence).
Primary sources
Used as evidence for
This is an original summary from the Tinnitus Evidence verified database, checked against the primary source — not a reproduction of the publisher's abstract.