Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry (first human pilot)
Record details
- Authors: Marks KL, …, Shore SE.
- Journal / source: Science Translational Medicine (2018)
- Design: Randomized crossover pilot
- Sample: 20
- Primary endpoint: Loudness and TFI
- Randomized: Yes · Sham/placebo-controlled: Yes · Independent of the manufacturer: Yes
What this research found
Reduced tinnitus loudness and TFI vs auditory-only; established the timing-dependent plasticity approach in humans.
Limitations and conflicts of interest
Pilot size.
Funding / conflicts: NIH-funded; investigator patent interests disclosed.
Primary sources
Used as evidence for
This is an original summary from the Tinnitus Evidence verified database, checked against the primary source — not a reproduction of the publisher's abstract.