Low-level laser therapy for tinnitus: meta-analysis with trial sequential analysis

Record details

Authors: Chen CH, et al.
Journal / source: Brain Sciences (2020)
Design: Meta-analysis + trial sequential analysis
Sample: 11 RCTs, N=670
Primary endpoint: Tinnitus outcomes
Randomized: Yes · Sham/placebo-controlled: Yes · Independent of the manufacturer: Yes

What this research found

No significant benefit of LLLT on tinnitus severity (MD −2.85, 95% CI −8.99 to 3.28, p=0.362; 11 RCTs, N=670). The authors' own conclusion: the value of LLLT 'remains unclear', in part due to small patient numbers and heterogeneity, and larger studies are called for.

Limitations and conflicts of interest

See the record summary above.

Funding / conflicts: Independent.

Primary sources

Used as evidence for

Low-level laser therapy / photobiomodulation

This is an original summary from the Tinnitus Evidence verified database, checked against the primary source — not a reproduction of the publisher's abstract.